November 18, 1988 |
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7.00 |
Reception, Greenville Room, Hilton Inn |
8.00 |
Dinner, Hilton Inn |
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November 19, 1988 |
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Morning session: |
Methodological and Philosophical
Issues (Chair: Reidar Lie) |
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9.00 |
Welcome and Introduction
Reidar K. Lie, East Carolina University
Jochen Schaefer, IIfTC, FRG |
9.15 |
William Dupont, Ph.D.: Sequential
stopping rules and sequentially adjusted F-values. Does one require
the other? |
9.45 |
Fred Gifford, Ph.D.: Stopping rules: An
assessment of proposals by Meier and Kadane |
10.15 |
Coffee |
10.45 |
Teddy Seidenfeld, Ph.D.: On the ethics
of a new clinical trial |
11.15 |
Kenneth Schaffner, M.D., Ph.D.: Statistical
and individual concepts of causation |
12.00 |
Luncheon (Brody Building, ECU School of Medicine, 2W-38) |
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Afternoon session: |
Clinical experience (Chair:
Jochen Schaefer) |
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13.30 |
Arthur Moss, M.D.: Interpretation
and significance of two or three way interactions in clinical trials |
14.00 |
Bert Spilker, M.D., Ph.D.: Who interprets
clinical data: clinician or statistician? |
14.30 |
Larry Friedman, M.D.: Selected design
issues in cardiovascular clinical trials |
15.00 |
Coffee |
15.30 |
Franz Ebner, M.D.: Problems in the
translation of clinical trials to clinical practice |
16.00 |
Rein Vos, M.D.: The paradox of generating
and validating clinical hypotheses |
16.30 |
Discussion and concluding remarks |
17.15 |
Transportation back to hotel |
19.00 |
Dinner, King and Queen, 103 Eastbrook Drive |
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November 20, 1988 |
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Discussion (Chair: Kenneth
Schaffner) |
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9.00-11.30 |
Informal discussions among the participants of the symposium |
11.30 |
Lunch |
13.00 |
Departure from Greenville |